Your eyes are the windows to your soul, and lutein and astaxanthin are highly related members of a type of carotenoid called xanthophylls that are very important to the health of your eyes. As a complement to vitamin E, both lutein and astaxanthin can function as strong antioxidants in the membranes of your tissue cells. Although the sources of lutein and astaxanthin in your diet may be quite different, lutein and astaxanthin have similar chemical structures and potential health benefits.
Bioavailability
Lutein is a yellowish carotenoid pigment, and good sources include kale, turnip greens, spinach, Swiss chard and collard greens. Astaxanthin is a red-pink carotenoid produced by green microalgae in response to stress. However, you do not necessarily need to start collecting algae from the local pond. Astaxanthin is present in the fish that eat the small sea animals, which eat algae. Astaxanthin is also used as a coloring agent in seafood and as a feed additive in farm-raised fish. Lutein and astaxanthin are digested along with the fats in your diet, and both compounds are transported in your blood and distributed to your tissues as components of lipoproteins.
Eye Health
High levels of xanthophylls may be found in a region of the retina of your eyes called the macula. Algae produce astaxanthin as protection from ultraviolet radiation. Xanthophylls such as lutein, astaxanthin and zeaxanthin can similarly filter out and protect your eyes from harmful rays of ultraviolet and blue light, which may allow you to lose the shades and show off your pretty peepers more often when you are out in the sun. Harmful rays of light can eventually produce a condition called age-related macular degeneration, which causes vision deterioration and is common in the elderly. To avoid this, include food sources of xanthophylls in your diet to maintain your visual acuity as you grow older.
Cardiovascular Disease
Cardiovascular disease can cause a thickening in your artery walls, which can block the flow of blood through your heart and to your brain. Both lutein and astaxanthin may help to protect your arteries from thickening by acting as antioxidants and suppressing inflammation in your artery walls. A study published in the June 19, 2001 issue of “Circulation” found reduced thickening of the artery walls in human subjects with high levels of lutein in their blood. Similar studies in humans and experimental animals support a role for xanthophylls in curtailing the damaging effects of artery disease.
Cancer
Although human clinical studies of the relationship between dietary xanthophylls and cancer are scarce and largely inconclusive, the antioxidant activity of xanthophylls in pre-clinical experiments suggests that these compounds have the potential to curb cancer initiation and cancer cell growth. A study published in the December 2007 issue of the “European Journal of Cancer” reported lower incidence of skin cancer in human subjects with high dietary xanthophyll intake. At the very least, the ultraviolet light-filtering properties of xanthophylls may have cosmetic benefits to your skin, which may save you some money on makeup.
References
- Progress in Lipid Research: Proteins Involved in Uptake, Intracellular Transport and Basolateral Secretion of Fat-Soluble Vitamins and Carotenoids by Mammalian Enterocytes
- DSM Bright Science. Brighter Living: Astaxanthin
- Alternative Medicine Review: Astaxanthin, Cell Membrane Nutrient with Diverse Clinical Benefits and Anti-Aging Potential
- The American Journal of Clinical Nutrition: The Putative Role of Lutein and Zeaxanthin as Protective Agents Against Age-Related Macular Degeneration -- Promise of Molecular Genetics for Guiding Mechanistic and Translational Research in the Field
- Circulation: Oxygenated Carotenoid Lutein and Progression of Early Atherosclerosis -- The Los Angeles Atherosclerosis Study
- Arteriosclerosis, Thrombosis, and Vascular Biology: Progression of Carotid Intima-Media Thickness and Plasma Antioxidants -- The Los Angeles Atherosclerosis Study
- Future Cardiology: Astaxanthin, Oxidative Stress, Inflammation and Cardiovascular Disease
- Molecules: Cancer Chemoprevention by Carotenoids
- European Journal of Cancer: Intake of Antioxidant Nutrients and the Risk of Skin Cancer
- Acta Biochimica Polonica: Cosmetic Benefits of Astaxanthin on Humans Subjects
Resources
Writer Bio
Michael Peluso is a semi-retired scientist in the field of nutritional biochemistry. He received his M.S. in nutrition from the University of California, Davis and Ph.D. in nutrition from the University of Missouri. Peluso's work has appeared in scholarly publications such as the "Journal of Nutrition," "Lipids" and "Experimental Biology and Medicine."